Some people with depression do not feel better even after trying several treatments. When this happens, they may be told they have treatment-resistant depression (TRD). It means their symptoms remain after trying at least two different antidepressants, taken at proper doses and for enough time.
This can be frustrating. Each new treatment might feel like a guess. But even when the usual methods do not work, other options can help. Clinics like isha.health offer support for people dealing with this kind of depression. Working with the right care team can make a big difference.
Understanding TRD
TRD is not rare. Many people with major depression don’t get full relief from standard medications or talk therapy. This does not mean help is out of reach. It just means a different plan is needed. Doctors must look at what has already been tried and what might work next.
