Understanding the Emerging Link
For years, depression has primarily been understood through the lens of neurotransmitter imbalances—serotonin, dopamine, and norepinephrine deficits. While this biochemical model remains valuable, growing research suggests that another system may play a significant role in the development and persistence of depressive symptoms: inflammation.
The field of psychoneuroimmunology—examining the relationship between the immune system and mental health—is shedding light on how systemic inflammation may contribute to mood disorders. This emerging understanding offers new avenues for more personalized, effective treatment strategies.
How Inflammation Impacts Mood
Inflammation is the body’s natural defense mechanism against injury or infection. However, when inflammation becomes chronic—due to factors such as stress, poor diet, medical conditions, or lifestyle factors—it can begin to negatively affect brain function.
